Fig. 5
From: Global pairwise RNA interaction landscapes reveal core features of protein recognition
The BIV DCA-scape accurately predicts mutational outcomes. a Identification of trans-activating regions in the BIV genome (red arrows and dotted line indicate the positions of the binding elements). b The secondary structure of the BIV TAR RNA. The lower portion of the element containing an essential bulge has the most favorable Hamiltonian score. c A comparison of mutational assays in the TAR bugle (left, Pearson’s R = 0.93) and lower stem (right, Pearson’s R = 0.77) to Hamiltonian scores55
