Fig. 3
From: Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells
Probes with high PC2 affect differentiation, cell-cycle arrest and mTOR signalling activity. a Summary of significantly (p < 0.01, FDR 1%, t-test, Supplementary Fig. 17) affected molecular phenotypes from probes with high PC2 (top 10%) compared to low PC2 (bottom 10%). b Scatterplot illustrating probes with high PC2 score (x-axis) have increased TGM1 and NOTCH1 levels measured by ID-seq. c Scatterplot illustrating probes with high PC2 score (x-axis) have increased cell-cycle arrest marker (Cyclin B1 and p-cdc2) levels measured by ID-seq. d Scatterplot showing the probes with high PC2 score (x-axis) strongly have decreased phospho-S6 and phospho-mTOR levels illustrating decreased mTOR signalling activity measured by ID-seq
