Fig. 1 | Nature Communications

Fig. 1

From: Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease

Fig. 1

Schematic experimental design showing infection and sampling timeline for the four pregnant rhesus macaques in the study. Pregnant macaques, identified by gestation day (GD) of inoculation, were intravenously (IV) and intraamniotically (IA) inoculated with 5 log10 PFU of Brazilian ZIKV strain SPH/2015 in the first or second trimester of pregnancy. Sample collection and ultrasound-monitoring schedules, originally intended until near term at GD155, are noted. CSF is cerebrospinal fluid, dpi is days post inoculation. Animal color scheme is consistent for other figures. Not shown are the three GD-matched animals that were sham-inoculated and sampled on the same schedule as the ZIKV-inoculated macaques

Back to article page