Fig. 2
From: ATR is a multifunctional regulator of male mouse meiosis
Mid-pachytene germ cell elimination is preserved in mice deficient in the PIKKs. Western blot showing a ATR and b ATM depletion in mice with different PIKK mutations. c γH2AX (magenta) and SYCP3 (green) immunostaining (n = 2 males, 25 cells for each stage) and d stage IV elimination in Atrfl/– Atm−/− males. e γH2AX and SYCP3 immunostaining (n = 2 males, 25 cells for each stage) and f stage IV elimination in Atrfl/– Atm fl/– Prkdcscid/scid males. Scale bar 20 µm in d, f and 10 µm in c, e
