Fig. 9

Human brain-specific network of 16p11.2 gene interactions. This network displays human brain-specific genetic interactions of all tested 16p11.2 genes and modifier genes, as well as neighboring connector genes. Network nodes with thick borders represent tested genes, with node shape representing gene category. The size of the nodes is proportional to how many connections they have in the network, and the thickness of the edges is proportional to the number of critical paths in the network using that edge. Purple nodes are genes annotated with cell proliferation or cell cycle GO terms