Fig. 7
From: Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa
pmrB mutations are found in patient isolates and are associated with lysozyme resistance. Three isolates from one patient (a) and seven from another (b) were compared for lysozyme resistance. Isolates with at least one pmrB mutation are in red (49194 = R202H, 49137 = I73L, E82K, E225Q). (a, b) Growth in the presence of lysozyme expressed as a percentage of growth in LB (OD600). Data are presented as mean ± s.d. and are a composite of three independent experiments with each isolate run in triplicate. **p < 0.01, ***p < 0.005, ns non-significant, vs. 49194 (a) or 49137 (b) in ANOVA analysis performed on OD600 with lysozyme as a covariant
