Fig. 5

Fluctuations can be predicted from pre-stimulus LFP and in turn predict behavior. a To assess the relation between the LFP prior to sound onset and the spiking response after sound onset, we assigned each dual-sound trial to one of two groups, A-like or B-like, based on whether the spike count matched the response to single-sound A or B (see Methods). We then compared the average LFP voltage (without filtering for any particular frequency band) of the two groups. The average LFP (mean ± SE) is shown in blue for 1917 trials classified as A-like (A = contralateral sound) and in red for 1565 trials classified as B-like. The traces are significantly different in the 600 ms before sound onset and in the 600 ms after sound onset (two-tailed t-test, p < 0.01). b–d The target of the first saccade on dual-sound trials can be predicted by the spike count during sound presentation. b Eye trajectories during dual-sound trials to the same pair of single-sounds (one triplet). The traces are color-coded based on which of the two sounds the monkey looked at first in the response sequence. For clarity, all traces are aligned on a common starting position despite some variation in fixation accuracy. c The average assignment score of trials in which the monkey looked at sound A first is more A-like than that of trials in which the monkey looked at sound B first. Bars indicate SEM; p value is for a two-tailed t-test involving a total of n = 1171 trials. d The relationship between assignment score and first saccade target was also evident at the scale of 50 ms bins (green = positive correlation; *p < 0.05 for t-test of assignment score on A-first vs. B-first trials)