Table 1 Summary table of clinical characteristics of patient donors

From: Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

ID

Age

Sex

Stage

Chemotherapy regimen

TRG

Differentiation

CAM298

58

M

ypT1bN0M0

ECX

2

Well

CAM388

78

M

ypT2N0M0

ECX

4

Moderate to poor

CAM247

67

M

ypT2N2M0

ECX

4

Moderate

CAM292

66

F

ypT3N1MX

ECX

4

Moderate to poor

CAM296

72

M

ypT3N3MX

ECF

4

Moderate to poor

CAM338

51

F

ypT3N1MX

ECX

5

Moderate to poor

CAM401

77

F

ypT4aN2M0

CF

5

Poor

CAM412

52

F

cT1bN0M0

No chemotherapy

No chemotherapy

Poor

CAM277

80

F

cT3N2M0

No chemotherapy

No chemotherapy

Poor

CAM408

60

M

cT1aN0M0

No chemotherapy

No chemotherapy

Moderate

  1. The tumor regression grade (TRG) was used to describe histopathological response to chemotherapy, whereby 1 indicates complete regression and 5 is defined as no regressive changes. Patients are ranked by TRG
  2. The acronyms for the chemotherapy regimens are: ECX Epirubicin, Oxaliplatin, Capecitabine, ECF Epirubicin, Cisplatin, 5-Flourouracil, EOX Epirubicin, Oxaliplatin, Capecitabine, and CF Cisplatin, Fluorouracil