Fig. 7 | Nature Communications

Fig. 7

From: Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

Fig. 7

SMC1A and SMC3 enrichment at the paternal Kcnq1ot1 ICR reduced upon nucleoporin depletion. Quantitative ChIP analysis and allelic analysis for a SMC1A and b SMC3 at positive mAb414 and NUP153 enrichment sites in control and Nup107/Nup62-double, Nup98/96- (IC3, IC4 only) and Nup153-depleted XEN cells (n = 3 biological samples with three technical replicates per sample). Allelic proportions are represented as a percent of the total enrichment level. Error bars, s.e.m.; *, significance p < 0.05 compared to the siNT control (t test)

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