Fig. 4

Unique cytosolic domains and interactions. a Side and top views of the cytosolic domains including full-length N- and truncated C-terminal domains. b Ribbon diagram of the tetrameric coiled-coil domain structure. Side chains are represented by ball and stick models. c Helical wheel projection of the residues in the coiled-coil domain of TRPC4. d–f Side views of a single subunit of the N-terminal domain to illustrate the locations of the interactions between the (e) TRP domain (blue) and N-terminal domain (orange) and (f) N-terminal domain (orange) and truncated C-terminal domain (purple)