Table 4 Longitudinal analysis of differentially remodeled genes

From: Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

ProbeID	Chr	Pos	Persistent allergics (n = 49)				Transient allergics (n = 115)				Gene
			Deltabeta (FU-BL)	Adj.P value deltabeta	Log FC (FU-BL)	Adj. P value log FC	Deltabeta (FU-BL)	Adj. P value deltabeta	Log FC (FU-BL)	Adj. P. val log FC
cg20995327	Chr12	12,595,583	0.172	0.000	−0.248	0.178	0.025	0.051	0.145	0.296	LOH12CR 1
cg22152180	Chr2	238,904,315	0.079	0.000	0.134	0.536	0.026	0.095	0.125	0.296	UBE2F
cg09775648	Chr3	111,314,102	0.115	0.000	−0.179	0.611	0.058	0.095	−0.425	0.001	ZBED2
cg26319797	Chr2	190,309,186	0.148	0.000	−0.529	0.012	0.030	0.095	−0.114	0.467	WDR75
cg24278087	Chr11	44,597,119	0.072	0.000	−0.196	0.428	0.014	0.101	−0.088	0.591	CD82
cg05175803	Chr17	78,765,948	0.136	0.000	−0.230	0.323	0.025	0.141	−0.154	0.390	RPTOR
cg27403618	Chr1	209,907,350	0.078	0.000	−0.549	0.428	0.027	0.160	−0.213	0.627	HSD11B1
cg12592365	Chr16	15,583,606	0.100	0.000	−0.408	0.345	0.042	0.160	−0.075	0.612	C16orf45
cg02660643	Chr2	69,735,185	0.097	0.000	0.023	0.931	0.016	0.160	−0.033	0.758	AAK1
cg14174367	Chr17	17,599,543	0.085	0.001	−0.189	0.428	0.027	0.197	−0.289	0.001	RAI1
cg25279613	Chr8	145,022,842	0.056	0.001	0.245	0.498	0.029	0.197	−0.104	0.467	PLEC
cg17355385	Chr2	158,712,427	0.068	0.001	0.030	0.931	−0.022	0.245	−0.089	0.758	ACVR1
cg20930706	Chr1	172,558,180	0.055	0.001	0.141	0.428	0.026	0.455	−0.071	0.607	SUCO
cg15928524	Chr3	111,314,186	0.055	0.001	−0.179	0.611	0.016	0.464	−0.162	0.296	ZBED2
cg00545580	Chr6	154,560,711	0.092	0.002	0.695	0.012	0.014	0.556	−0.075	0.612	IPCEF1
cg22992505	Chr20	62,368,837	−0.073	0.003	−0.059	0.931	0.011	0.568	−0.034	0.758	LIME1
cg03116016	Chr7	24,956,523	0.079	0.004	0.000	0.998	0.007	0.805	0.046	0.774	OSBPL3
cg24323726	Chr11	65,904,369	0.024	0.009	−0.181	0.428	−0.006	0.805	0.089	0.758	PACS1
cg04599190	Chr17	78,571,214	0.061	0.018	−0.230	0.323	0.002	0.805	−0.039	0.758	RPTOR
cg00957665	Chr14	99,684,844	0.029	0.019	0.049	0.850	0.005	0.805	−0.228	0.027	BCL11B
cg25867265	Chr2	145,182,344	0.034	0.023	−0.228	0.536	−0.005	0.805	0.295	0.106	ZEB2
cg11903019	Chr1	202,128,508	0.051	0.025	−0.428	0.006	−0.009	0.805	0.349	0.053	PTPN7
cg16001422	Chr16	87,491,587	0.026	0.029	0.255	0.323	0.004	0.876	−0.102	0.719	ZCCHC1 4
cg21410897	Chr10	104,406,345	0.033	0.040	−0.323	0.049	0.003	0.876	0.124	0.390	TRIM8
cg10502206	Chr5	66,306,763	0.007	0.384	−0.168	0.464	0.002	0.896	−0.081	0.758	MAST4
cg25298754	Chr1	66,737,176	0.015	0.469	0.624	0.018	−0.001	0.999	0.089	0.758	PDE4B

Change in DNA methylation (deltabeta) and gene expression (log FC) from baseline to follow-up are shown
BL: baseline; FU: follow-up

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Table 4 Longitudinal analysis of differentially remodeled genes

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