Table 2 Verified lipid species that significantly differ in plasma and liver samples between GF and SPF mice
From: The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
Lipid species | Lipid class | Matrix | Log FC Exp.1 GF = 6; SPF = 6 | Log FC Exp. 2 GF = 12; SPF = 14 | p Exp. 1 | pExp. 2 |
|---|---|---|---|---|---|---|
FA16:1 n-7 FA20:3 n-6 FA22:6 n-3 | FA | Liver | 1.39 0.48 −0.40 | 0.31 0.18 −0.18 | 0.014 0.003 0.011 | 0.019 0.039 0.011 |
FA16:1 n-7 FA20:4 n-6 | FA | Plasma | 1.41 −1.09 | 0.36 −0.41 | 0.013 0.021 | 0.014 0.039 |
PC 32:0 PC 34:1 PC 36:1 PC 38:2 PC 38:3 PC O-36:1 PC O-36:4 | PC | Liver | −0.36 0.98 0.89 1.47 0.61 0.56 −0.55 | −0.22 0.34 0.33 0.52 0.36 0.18 −0.24 | 0.006 0.009 0.014 0.019 0.011 0.006 0.030 | 0.018 0.029 0.002 0.001 0.002 0.010 0.017 |
PC 34:1 PC 38:3 PC O-38:4 | PC | Plasma | 1.17 0.55 −0.60 | 0.35 0.17 −0.36 | 0.004 0.024 0.017 | 0.004 0.006 0.014 |
LPC 20:3 | LPC | Liver | 1.18 | 0.47 | 0.005 | 0.002 |
LPC 20:3 | LPC | Plasma | 1.14 | 0.30 | 0.006 | 0.000 |
PE 32:0 | PE | Liver | −0.41 | −0.55 | 0.041 | 0.001 |
PE 38:5 | PE | Plasma | 0.31 | 0.21 | 0.030 | 0.039 |
PE P-18:0/20:4 | PE P | Liver | −0.50 | −0.17 | 0.011 | 0.021 |
PE P-16:0/20:4 PE P-16:0/22:6 PE P-18:0/20:4 PE P-18:0/22:6 | PE P | Plasma | −0.91 −1.20 −0.95 −1.33 | −0.32 −0.45 −0.26 −0.45 | 0.013 0.010 0.032 0.029 | 0.003 0.004 0.039 0.003 |
PI 36:2 PI 40:6 | PI | Liver | −1.16 −0.92 | −0.91 −0.88 | 0.001 0.005 | 0.000 0.000 |
PI 36:4 PI 40:6 | PI | Plasma | 0.23 −0.75 | 0.38 −0.76 | 0.038 0.003 | 0.000 0.000 |
CE 20:4 | CE | Liver | −0.65 | −0.29 | 0.014 | 0.007 |
CE 20:3 CE 20:4 | CE | Plasma | 0.95 −0.72 | 0.32 −0.35 | 0.017 0.017 | 0.018 0.006 |
