Fig. 3 | Nature Communications

Fig. 3

From: A high throughput screen for next-generation leads targeting malaria parasite transmission

Fig. 3

Chemical structure of GHCDL compounds selected for further study. Five compounds showing a range of transmission-blocking activity at the profiling stage were selected for detailed study. DDD01027599 (found to actually be BPCA—see Supplementary Fig. 1-2) and DDD01245291 are active against gametocytes and asexuals; DDD01255968 and DDD01249504 are active specifically against male gametocytes; and DDD01035881 specifically targets male gamete formation

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