Fig. 4
From: Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens
Synthesis of fragments 3a–c and X-ray crystal-structure diagrams of 3a, 3b, and 3c'. Reagents and conditions: a IBX (2.0 equiv), CH3CN, 55 °C, 5 h; b 24 (1.1 equiv), LDA (1.1 equiv), THF, −78 °C, then 2 M HCl, 3a: 86% (d.r. 4:1), 3b: 83% (d.r. 3:1), 3c: 75% (d.r. 3:1), (over 2 steps). IBX 2-iodoxybenzoic acid, LDA lithium diisopropylamide
