Fig. 5
From: Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens
Total synthesis of albomycins δ1, δ2, and ε. Reagents and conditions: a HATU (1.5 equiv), DIPEA (2.0 equiv), DMF, −15 °C, 2 h, 25a: 93%, 25b: 91%, 25c: 90%; b CAN (10.0 equiv), CH3CN/H2O, 30 min; c TFA, H2O, 1 h; d K2CO3, MeOH, H2O, 1a: 80% (over 2 steps), 1b: 72% (over 3 steps), 1c: 75% (over 2 steps). CAN ceric ammonium nitrate
