Fig. 2 | Nature Communications

Fig. 2

From: High-throughput chromatin accessibility profiling at single-cell resolution

Fig. 2

De novo identification of hematopoietic cell types by µATAC-seq. a Human PBMC isolation and µATAC-seq workflow. b Hierarchical (TF motifs) and k-means (cells) clustering of accessibility deviation z-scores across 2333 single cells (columns) of the 50 most variable TF motifs (rows). Colors correspond to cell types defined in a. c tSNE visualization of accessibility deviations at TF motifs for cells in b. Cells are either colored by cell type (upper left panel) or by the accessibility deviation z-score for the specified TF motif

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