Table 1 Optimization of reaction conditions

From: A general deoxygenation approach for synthesis of ketones from aromatic carboxylic acids and alkenes

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Entry

Variation of conditions

Yielda

1

None

72%

2

Without H2O

40%

3

No Ph3P

nd

4

1 mol% cat-II instead of cat-I

nd

5

2 mol% cat-III instead of cat-I

nd

6

2 mol% cat-IV instead of cat-I

nd

7

2 mol% cat-V instead of cat-I

nd

8

No photocatalyst

nd

9

No light

nd

  1. Standard conditions: photocatalyst I (1 mol%), 1a (0.2 mmol), 2a (1.5 equiv.), Ph3P (1.2 equiv.), K2HPO4 (20 mol%), DCM/H2O (2.0 mL, v/v = 4:1), rt, 5 W blue light-emitting diodes (LEDs), 48 h
  2. nd not detected
  3. aIsolated yield
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