Fig. 2
From: Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure
Overview of the extended gene-set analysis workflow. The workflow is composed of five steps, starting with a standard gene-set analysis in step one. Results from this analysis are then successively refined in the subsequent steps, discarding initially significant gene properties if their associations are found to be insufficiently robust. In the optional sixth step an exploratory interaction analysis is used to detect additional interaction effects not uncovered in the main analysis workflow
