Table 3 In vivo neutralization results for monoclonal IgG antibodies raised against Dp8 and oligoclonal IgG cocktails

From: In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies

 

Venom fractions

IgG ID

Dp8

Whole venom

 

2:1

4:1

6:1

1:1

2:1

3:1

4:1

366_01_A01

0/3

0/3

1/3

    

366_01_B06

0/3

0/3

0/3

    

366_01_C01

0/3

0/3

0/3

    

366_01_C09

2/3

2/3

0/3

    

367_01_F04

0/3

0/3

0/3

    

367_01_F07

1/3

0/3

3/3

    

367_01_F11

2/3

0/3

2/3

    

367_01_H01

3/3

3/3

3/3

  

1/4

 

367_01_H09

0/3

1/3

1/3

    

Cocktail 1

   

0/4

1/4

 

4/4

Cocktail 2

    

1/4

4/4

 

Cocktail 3

     

2/4

 

Cocktail 4

     

2/4

 
  1. Monoclonal IgGs and IgG cocktails were tested against individual venom fractions and whole venom using i.c.v administration. Numbers indicate survival ratios at 24 h. Ratios are provided as molar ratios between IgG:toxin.
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