Fig. 3
From: Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5
Rab11A SH3BP5 interface. a Zoom in on the binding interface of Rab11 and SH3BP5. Key Rab11 residues forming important interactions at the interface are labeled. b Alignment of the Rab11-binding site on both helix α1 and α4 of SH3BP5 and SH3BP5L along with paralogs from M. musculus (mSH3BP5), D. melanogaster (parcas), and C. elegans (REI-1/REI-2), with contact residues indicated by arrows. Red arrows indicate greater than 20 Å2 of buried surface area (BSA). c All interacting residues from both SH3BP5 and Rab11 are shown in stick representation and labeled, with the structures rotated and the interacting partner removed to allow for visualization. SwI and SwII are colored according to Fig. 2
