Fig. 5
From: Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins
Autophagy and MVBs both contribute to Fn14 trafficking. a–d WT or ATG4BDN stable expression HeLa cells were treated as follows and analyzed by confocal microscopy (scale bar, 20 µm): a treated with wortmannin as indicated and immunostained for Fn14 and p62; b transfected with siNT or siRNA against TRAF2 (siTRAF2), treated with TWK as indicated, and immunostained for Fn14. Arrows and arrowheads point at Fn14 at vesicles and plasma membrane, respectively; c, d transfected with siNT or siRNA against BECN1 (siBECN1) (c) or TSG101 (siTSG101) (d), treated with TWK, and immunostained for Fn14 and EEA1
