Fig. 5
From: Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Associations of genetic risk scores with hypothyroidism and hyperthyroidism. The y axis shows the probability of hypothyroidism (red) or hyperthyroidism (blue) with the p-value of the association test of the trait on the risk score. The x axis shows the percentage of risk alleles carried based on a weighted genetic risk score (GRS) built using the 61 TSH-associated (a) and 31 FT4-associated GWAS SNPs (b). The gray histogram shows the distribution of the GRS in the study sample