Fig. 2 | Nature Communications

Fig. 2

From: Differential lateral and basal tension drive folding of Drosophila wing discs through two distinct mechanisms

Fig. 2

Cell proliferation and the role of cell division for epithelial folding. a A wing imaginal disc of a 96 h after egg lay (AEL) larva carrying 48 h-old clones of cells marked by the expression of CD8-mCherry (Act5C > Gal4, UAS-CD8-mCherry, red). Adherens junctions are labeled by E-cad-GFP (gray). Scale bar is 10 μm. b Ratio of the average cell number per clone in the pouch and the average cell number per clone in the notum. Mean and s.e.m. are shown. n = 19 wing imaginal discs, 82 clones in the pouch region, and 59 clones in the notum region. c–j Top view (c, d, g, h) and cross-sectional (e, f, i, j) images of time-lapse movies of control (c–f) and Cdk1E1-24 mutant (g–j) cultured wing imaginal discs expressing E-cad-GFP are shown for the indicated time points after shift to the restrictive temperature. Scale bars are 10 μm

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