Fig. 3 | Nature Communications

Fig. 3

From: ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup

Fig. 3

Distinct DNA methylation pattern between A-D-M mutant and A-D-M WT PanNETs. a Unsupervised clustering of PanNETs using top 2000 variant CpG sites across all samples revealed two clusters. The two clusters separate A-D-M mutant from A-D-M WT PanNETs. b Principal component analysis using top 2000 variant CpG sites separated A-D-M mutant from A-D-M WT PanNETs along PC1

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