Table 1 Characterization of NMDAR EPSCs in the inhibitory neurons under various conditions

From: Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity

Time (ms)

Baseline- GNE-8324

GNE-8324

Baseline- Pip18

Pip18

Baseline- NAB-14

NAB-14

Baseline- Zinc

Zinc

Rise time (ms) (10–90%)

8.13 ± 0.92

8.23 ± 0.98

6.76 ± 0.32

6.99 ± 0.44

9.89 ± 3.50

10.08 ± 5.10

7.04 ± 1.08

6.27 ± 0.52

τ

52.29 ± 7.5

44.81 ± 7.08

44.69 ± 8.479

45.69 ± 8.40

63.94 ± 11.28

64.94 ± 9.68

71.22 ± 10.48

84.25 ± 16.88

  1. n (GNE-8324) = 12, n (Pip18) = 7, n (NAB-14) = 6, n (Zinc) = 5
Back to article page