Fig. 1
From: Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies
A 5 h time window for learning and associative binding. a Time window to complete MWM learning. Left: latencies as a function of time interval between first and second group of two trials on Day1. Two-way RM ANOVA, Interaction, P < 0.0001, n = 5, 8, 5, 5, 5; right: PV plasticity (low-PV contents in vH at 24 h; Ctrl: swim control without platform); One-way ANOVA, P < 0.0001, n = 7, 5, 11, 5, 5. Tr. trial, x numbers of hours as indicated in different protocols; Day2: 4 trials. b Associative binding of neutral object to fear memory during 5 h time unit. x number of hours following acquisition of cFC. Schematic: boxes of different colors indicate different contexts; object: Falcon tube. Left, center: Representative heat maps (left) and quantitative analysis (center; one-way ANOVA, P < 0.0001, n = 5, 9, 5, 5, 5, 5, 5, 5) of novel context exploration in the presence of object (Falcon tube; orange arrows). Right: Fear memory binding (3 h after acquisition) does not influence fear response to conditioning context (tested at 26 h; unpaired t-test, t(19) = 0.8568, P = 0.4022, ns, n = 12, 9). Error bars: SEM; P < 0.05 (*), 0.01 (**), 0.001 (***), 0.0001 (****). For a more detailed description of the statistical analysis please refer to Supplementary Table 1
