Fig. 5
From: Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery
Effect of HFD on the development of pancreatic ACC in Ngn3-Tsc1−/− mice. a Pancreatic ACC incidence. b Pancreatic weight Ngn3-Tsc1−/− (KO) mice at 6-weeks-old were fed with 45% HFD or NCD for 4, 6, and 8 weeks. Animals were sacrificed and pancreas assessed for ACC. n = 8 and 7 for 70-days-old KO mice fed HFD or NCD for 4 weeks, respectively; n = 11 and 7 for 84-days-old KO mice fed HFD or NCD for 6 weeks, respectively; n = 7 and 6 for 98-days-old KO mice fed HFD or NCD for 8 weeks, respectively. Values are mean ± SEM. *P < 0.05 Ngn3-Tsc1−/−(KO) HFD vs. Ngn3-Tsc1−/−(KO) NCD
