Fig. 6
From: Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling
CCRR improves gap junction communication in AC16 human heart cells. AC16 human adult ventricular cardiomyocytes were loaded with a diffusible fluorescent dye (Lucifer yellow), and the diffusion of the dye was monitored under a laser confocal microscope (200× magnification). Note that CCRR overexpression after infection of Lv-CCRR significantly promoted, whereas CCRR knockdown by Lv-siCCRR nearly completely blocked, the diffusion of Lucifer yellow among AC16 cells (green). The high molecular weight marker dye conjugate Rhodamine B was used as a negative control (red). Similar data were acquired from another three independent experiments
