Fig. 4
From: A missense variant in SLC39A8 is associated with severe idiopathic scoliosis
Skeletal abnormalities and growth deficit in slc39a8−/− zebrafish. a Thoracic and caudal vertebral malformations causing mild spinal curvature in slc39a8−/− zebrafish (bottom) compared to WT (top) stained with alizarin red. Magnified images show vertebral fusions in KO fish. Scale bar 5 mm. b slc39a8−/− zebrafish have more spinal abnormalities than WT fish. c Reduced length of slc39a8−/− zebrafish (N = 20) compared to wild-type (N = 20) at 9 mpf ***p < 10−6, t-test. Lines are mean, first and third quartiles
