Table 1 Association of rs13107325 with adolescent idiopathic scoliosis

From: A missense variant in SLC39A8 is associated with severe idiopathic scoliosis

 

Number of samples

MAF

  

Group

Case

Control

Case

Control

P-value

OR (95% CI)

AIS GWAS

457

987

0.14

0.08

1.60 × 10−7

2.01 (1.54–2.62)

AIS replication

841

1095

0.11

0.06

9.97 × 10−9

2.00 (1.57–2.57)

Combined

1314

2082

0.12

0.07

7.02 × 10−14

1.94 (1.63–2.34)

  1. MAF = minor allele frequency, OR = odds ratio, CI = confidence interval, AIS = adolescent idiopathic scoliosis
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