Fig. 2
From: Hidden hearing loss selectively impairs neural adaptation to loud sound environments
Inferior colliculus recordings to investigate adaptive coding. a, b Examples of frequency–response areas of IC multi-unit clusters from a control (a) and a noise-exposed mouse (b). c Distribution of characteristic frequencies of IC multi-unit clusters (black—control, 91 multi-unit clusters recorded from eight mice; red—noise-exposed, 142 multi-unit clusters from ten noise-exposed animals). The range of characteristic frequencies was similar in both groups, and the mean characteristic frequencies were not significantly different. d Illustration of the switching stimulus to investigate adaptive coding. Stimulus levels are shown in the right panel for two switch periods, and corresponding distributions of sound levels for the two HPRs (centred on 44 and 80 dB SPL) are shown on the right. e, f Examples for adapted rate-level functions (solid lines) and fits with a broken-stick hyperbolic tangent (dashed lines) for the switch stimulus with HPRs centred at 56 and 80 (left) or 68 and 80 dB SPL (right, HPRs are indicated by the coloured areas). Data from a control animal is shown in e and from a noise-exposed animal in f
