Fig. 6 | Nature Communications

Fig. 6

From: Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes

Fig. 6

Enrichment analyses of genes related to liver, brain and adrenal gland for Alzheimer’s disease. Shown are the tissue-based gene sets with the strongest enrichment signals for Alzheimer’s disease. Each gene set was analyzed twice: the left panel corresponds to the analysis based on the original gene set; the right panel corresponds to the analysis where SNPs within 100 kb of the transcribed region of any gene in Apolipoproteins (APO) family (Methods) were excluded from the original gene set. Dashed reddish purple lines in both panel denote the same Bayes factor threshold (1000) used in the tissue-based analysis of all 31 traits (Table 3). HE highly expressed; SE selectively expressed; DE distinctively expressed

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