Fig. 5
From: Sources, propagation and consequences of stochasticity in cellular growth
Condition-dependence of antibiotic responses. a Ribosomal content per cell as a function of average growth rate after treatment with chloramphenicol. Predictions (solid lines) are in quantitative agreement with experimental data9 (dots, shaded areas denote standard deviations over replicates and colours denote different nutrient conditions). b For any given nutrient condition the average growth rate is predicted to decrease monotonically with antibiotic dose. c Growth heterogeneity is predicted to be highly complex in a both nutrient- and dose-dependent manner. In nutrient-rich conditions growth heterogeneity increases with antibiotic dose, while in intermediate and poor conditions the response is non-monotonic. Over a large range of nutrient conditions there exists a non-zero drug dose that minimises growth heterogeneity (solid white line, b, c)
