Fig. 2 | Nature Communications

Fig. 2

From: Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

Fig. 2The alternative text for this image may have been generated using AI.

Expressional aberration of inflammation-related genes associated with NASH development in HFHC-fed mice. a Clustering of differentially expressed genes in HFHC-induced NASH as compared to HF-induced steatosis. b Pathways enriched by differentially expressed genes in NASH vs. steatosis. #gene, the number of annotated genes in the input list / number of annotated genes in the reference list. adjP, p value adjusted by multiple test adjustment. c Differentially expressed inflammatory genes in NASH compared to steatosis. Expression levels were normalized to the mean level of each gene among all samples shown. d Schematic illustration of the dysregulated pathways involved in the development of HFHC-induced NASH

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