Fig. 4 | Nature Communications

Fig. 4

From: Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

Fig. 4The alternative text for this image may have been generated using AI.

Aberrant gene expression verified in human NASH-HCC samples as compared to adjacent non-tumor livers. a Shown are RNA levels in FPKM in 17 pairs of tumors compared to adjacent non-tumor livers from patients with NASH-HCC. P values by paired t tests and FDR adjusted by Benjamini–Hochberg method are shown. Expression levels were normalized to the mean level of each gene among all samples shown. b Expression of seven genes was further validated to be significantly altered in 12 pairs of NASH-HCCs (T) compared to adjacent non-tumor livers (N) by RT-qPCR. Comparison by paired t tests

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