Fig. 3

Population layer specificity of coherence during cue and delay periods. a Schematic drawing of dynamic laminar flow conveying target recall signal. b, c Laminar pattern of coherence (mean ± s.e.m.) with neurons showing significant signal contents [pair-recall index (PRI)/pair-coding index (PCI)]. *, P < 0.05; comparison with zero by paired t-test corrected for multiple comparisons. ^†, P < 0.05; main effect or interaction in ANOVA. d Diagram for estimation of laminar transition of inter-areal coherence. Coherence profiles (two periods × two frequency ranges × 13 layers for each dataset) were classified into clusters according to k-means clustering in the principal component (PC) space. See Methods and Supplementary Figure 5a for details. e Scatter plot for first three PC values of individual datasets. n = 56. Each dataset is color-coded for the clusters determined by k-means clustering (red = cluster 1, blue = cluster 2, green = cluster 3; note that red open circle depicts data in Fig. 2). f Population dynamics of layer specificity in coherence (ordinate) from the cue (left) to the delay (right) periods, as a function of frequency (abscissa). n = 19, 24, and 13 for clusters 1, 2, and 3, respectively. g Laminar dynamics of coherence (mean ± s.e.m.) at 10−25 (black solid line) and 25−40 (gray dotted line) Hz from the cue (left) to the delay (right) periods. *, P < 0.05; **, P < 0.01; and ***, P < 0.001; comparison with zero by paired t-test corrected for multiple comparisons. ^†, P < 0.05; paired t-test corrected for multiple comparisons. Right inset for each cluster summarizes the layer specificity of inter-areal coherence during the cue (brown) and the delay (purple) periods. h Signal content of A36 neurons in each cluster (mean ± s.e.m.). *, P < 0.05; Tukey−Kramer test after one-way ANOVA. i Summary schema for laminar transition of inter-areal coherence for target recall (cluster 1) and pair-coding (cluster 2) signals. IG infragranular layer, SG supragranular layer