Fig. 3
ZFP296 co-localizes with NuRD and SIN3A in ESCs. a Venn diagrams summarizing the overlap between GFP-ZFP296 peaks and NuRD or SIN3A ChIP-seq results in ESCs. b Heat map showing the ChIP-seq read density for input, GFP-ZFP296, MBD3, CHD4, and SIN3A, centred on GFP-ZFP296 ChIP-seq peaks. c Top three most significant motifs enriched under GFP-ZFP296 ChIP-seq peaks. d GO term enrichment analysis of Biological Processes for genes within 100 kb of a GFP-ZFP296 peak (nearest gene only). e Band plot of four different histone marks and p300 (publicly available data19) at GFP-ZFP296 binding sites. f Genomic distribution of GFP-ZFP296 ChIP-seq peaks in ESC compared to a set of random regions (n = 3102) of the same average length. TSS peaks were +5 kb/−1 kb from a transcription start site. *p < 0.05, as assessed by Chi-squared test
