Fig. 3
From: Proteome evolution under non-substitutable resource limitation
Protein expression level heatmaps and annotation for the differentially expressed proteins. Both divergent and convergent responses were divided into upregulated and downregulated functions based on the mean expression level of each protein across the treatments (marked below the heat maps). Annotation from GO Biological Processes was available for 166 of 351 proteins. Positive convergent and divergent responses were significantly enriched in photosynthesis- and ribosome-related proteins (DAVID Functional Enrichment Analysis p < 0.01). Negative convergent responses were significantly enriched in proteins related to carbon metabolism, ATP binding, pyridoxal phosphate-dependent transferases, fatty acid degradation-related proteins, and plant-type vacuolar proteins (DAVID Functional Enrichment Analysis p < 0.01). Negative divergent responses had no significantly enriched proteins. Additionally, we note that two proteins related to methionine metabolism are upregulated in the low-phosphate (P) treatment but downregulated in all others. An asterisk (*) indicates that the control is significantly different from zero (t test p < 0.05), indicative of adaptations to chemostatic conditions
