Fig. 6
From: Gene inversion potentiates bacterial evolvability and virulence
Across phyla, HO genes are enriched in fewer and consistent functions. a The relative number of functions identified as enriched among co-directional (CD) vs. head-on (HO) genes is highly consistent across phyla. The number of functions found to be enriched among CD or HO genes was determined for 12 species (listed in the Methods section), then averaged across species. Error bars represent the standard error of the mean. Student’s t test was used calculate statistical significance, **p value = 0.0004. b The functions of all lagging strand (head-on) or leading strand (co-directional) genes were determined on a per species basis. Functions found to be enriched in ≥4 organisms were included here as consensus functions
