Fig. 8 | Nature Communications

Fig. 8

From: Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

Fig. 8

ERα-mediated control of gene expression signatures. a Heatmap of RNAseq transcriptomic analysis of WT.GFP+ and ERα−/−.GFP+ MECs that grew intraductally in NSG females contralateral glands. Row Z scores of genes that were differentially expressed are included. b, c Gene set enrichment analysis of genes that were down-regulated, in in ERα−/−.GFP+ MECs compared to WT.GFP+ control cells. By hallmark gene sets (b) and curated gene sets (c). The most significantly enriched terms with p values are listed

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