Fig. 3
From: Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
Characterization of the baseline level of G4-RNA landscape using G4RP-seq. a Top 10 highly abundant transcripts (filtered by at least 500 base-read counts) with the lowest BioTASQ enrichment (blue bars, normalized to the input in the untreated sample) or with the highest BioTASQ enrichment (red bars) ranked by Enrichment Scores. b Regression plot of BioTASQ-Enrichment Score for each transcript versus its corresponding G/C content (R2 = 0.187, p < 0.001, significant non-zero relationship). c Regression plot of BioTASQ-Enrichment Score for each transcript versus its corresponding gene length (R2 = 0.00005, p = 0.89, non-significant relationship). d Number of pG4 motifs (calculated by Quadbase2 using mid stringency G3L1–7) to gene length ratio plotted against the subset of highly abundant transcripts ranked by their BioTASQ enrichment. The bar graph (inset) shows the average pG4 motif/gene length ratio between the top 100 ranked transcripts versus the bottom 100 ranked transcripts (p < 0.001, significant difference, Student's t-test)
