Fig. 3
From: Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
Frequency of neurotransmitter-brain region pair response upon compound administration. Our analysis highlights the fraction of times compound administration led to an increased (red) or decreased (blue) neurochemical response across each brain region and neurochemical component pair. The visualization contains a total of 1813 compound measurements available across 44 distinct brain regions. It can be seen that neurochemical components such as dopamine (DA) have high frequency of upregulation across different brain regions, indicating a rather unspecific response of this neurotransmitter to drug treatments. Missing measurements are coloured in grey, which also highlights the sparsity of the neurochemical experiments. Neurochemical components are ordered by classification (indicated via row colouring)
