Fig. 4 | Nature Communications

Fig. 4

From: Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs

Fig. 4

Compound activity across brain regions and neurotransmitters. The analysis highlights that the historical classification of active ingredients of drugs (ATC codes) does not cluster well with their actual mode of action. There is little correlation between compound activity and codes which hence indicate that the current classification system is not exhaustive or complete. A subset of the compounds is shown here upon filtering the database for matrix completeness of 50%. ATC codes are shown using colour (key above). Compounds discussed in the main text are outlined using *

Back to article page