Table 2 Clinical characteristics of patients with fibrotic interstitial lung disease

From: STING-dependent sensing of self-DNA drives silica-induced lung inflammation

Patient

Age

Gender

Treatment

FEV1 l

FEV1% predicted

Diagnosis

Smoking history: pack years/years of smoking cessation

A

63

Male

Esbriet

1.93

52.5

Fibrotic ILD

25 PY/15 Y cess

B

40

Female

No

No

No

Fibrotic ILD

n.d.

C

48

Male

No

n.d.

n.d.

Fibrotic ILD

0 PY

D

41

Female

No

n.d.

n.d.

Fibrotic ILD

0 PY

E

57

Male

Esbriet

1.5

43

Fibrotic ILD

35 PY/7 Y cess

F

65

Male

Cortisone 25 mg

1.1 l

39

Fibrotic ILD

70 PY/ 6Y cess

G

63

Male

Esbriet

1.8

48

Fibrotic ILD

30 PY/12Y cess

H

60

Male

Cortisone 7.5 mg

2.3

64

Fibrotic ILD

30 PY/15Y cess

I

54

Female

n.d.

n.d.

n.d.

Fibrotic ILD

n.d.

J

68

Male

No

n.d.

n.d.

Fibrotic ILD

0 PY

K

52

Female

Ofev

1.6

58

Fibrotic ILD

35 PY/2Y cess

L

60

Male

No

2.4

60

Fibrotic ILD

40 PY/5Y cess

M

56

Male

Esbriet

1.51

43

Fibrotic ILD

0 PY

N

52

Male

No

2.7

70

Fibrotic ILD

45 PY/2Y cess

O

65

Male

No

1.65

57

Fibrotic ILD

25 PY/20Y cess

P

59

Male

No

1.6

45

Fibrotic ILD

0 PY

Q

50

Male

Ofev

1.73

435

Fibrotic ILD

20 PY/12Y cess

R

68

Male

Ofev

1.3

41.4

Fibrotic ILD

0 PY

S

63

Male

Esbriet

1.99

53

Fibrotic ILD

30 PY/3Y cess

T

65

Male

Ofev

1.48

38

Fibrotic ILD

10 PY/15Y cess

U

59

Male

Cortisone 5 mg

0.93

26.2

Fibrotic ILD

10 PY/35Y cess

  1. FEV1 forced expiratory volume at 1.0 s, FEV1% ratio of FEV1 to FVC, forced vital capacity, FEV1% predicted FEV1% of the patient divided by the average FEV1% in the equivalent population, ILD interstitial lung disease, PY pack year, Y cess years of smoking cessation, n.d. not determined