Fig. 4

Heritability estimates and genetic correlations between epilepsy syndromes, calculated using LDAK. Subjects with a diagnosis of both CAE and JAE were excluded from both phenotypes. The genetic correlation coefficient was calculated with LDAK and is denoted with a color scale ranging from 0% (white) to 100% (red). #P < 0.05; *P < 0.0024 (Bonferroni threshold); \(h_L^2\)2 SNP-based heritability on liability scale (95% CI); †heritability estimate exceeded 100%, possibly due to small sample size and large SD; CAE - childhood absence epilepsy, JAE - juvenile absence epilepsy, JME - juvenile myoclonic epilepsy, GTCS alone - generalized tonic-clonic seizures alone, focal HS - focal epilepsy with hippocampal sclerosis