Fig. 8 | Nature Communications

Fig. 8

From: Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission

Fig. 8

Drp1-catalyzed fission on compositional mimics of the mitochondria and peroxisomes. a Representative images of Drp1 ± GFP on tubes and SLB with 5 mol% CL with and without Mff. Scale bar = 10 µm. b Ratios of Drp1 ± GFP and membrane fluorescence on the SLB and tubes; ****p < 0.0001, *p = 0.013, Mann–Whitney’s test. n(SLB) = 40 and n(tube) = 32 from a single experiment for apo. n(SLB) = 43 and n(tube) = 46 from a single experiment for GDP. n(SLB) = 27 and n(tube) = 23 from a single experiment for GMP-PNP. c Plot showing the percentage of tubes cut as a function of CL concentration on tubes with and without Mff. Data represents the mean ± S.E.M. of n(tubes) >50 for each condition

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