Fig. 2
Zelda accelerates gene activation regardless of transcriptional history a Representative images from the Graphical User Interface implemented for automatic tracking of nuclei across multiple divisions. Chromosomal splitting at the end of anaphase is automatically detected for each nucleus. b–d Quantification of transcriptional memory in various snaE < MS2 embryos. At each time point in nc14, the cumulative number of activated nuclei, expressed as a percentage of the total number of nuclei, is plotted after segregation into two populations: descendants of active mothers (green) and descendants of inactive mothers (red). The timing of activation of each nucleus has been normalized to its specific timing of mitosis. Temporal dynamics from snaE are depicted using solid curves, while those from transgenes with extra Zld-binding sites are represented as dashed curves (c, d)
