Fig. 3
From: Hierarchical and programmable one-pot synthesis of oligosaccharides
Examples of programmable one-pot synthesis. a Auto-CHO suggests that SSEA-4 can be synthesized with three BBLs: sialyl disaccharide 1 with RRV = 1462, monosaccharide 2 with RRV = 32.0, and reducing end acceptor 3 with RRV = 0. The calculated overall yield is 94% and the experimental yield is 43%. b Synthesis of a heparin pentasaccharide with differential protecting groups in color to allow selective introduction of the sulfate groups. c Synthesis of the oligoLacNAc module for the assembly of N-glycans with LacNAc repeats
