Fig. 2
From: Migration alters oscillatory dynamics and promotes survival in connected bacterial populations
A bacterial cross-protection mutualism serves as a model system to study migration-induced synchronization of population oscillations. a Diagram depicting the mutualistic interaction between ampicillin resistant (AmpR) and chloramphenicol-resistant (ChlR) cells. AmpR cells protect ChlR cells by enzymatically deactivating ampicillin, whereas ChlR cells protect AmpR cells by deactivating chloramphenicol. b Schematic illustration of the experimental growth-dilution scheme for growing isolated co-cultures in the absence of migration. Each day, cells are grown for 24 h and then diluted by a factor of 100 into fresh media and antibiotics. The total cell density as well as relative proportions of AmpR and ChlR cells are measured after 24 h of growth, before the dilution step. c Isolated co-cultures exhibit period-3 oscillations in the density of AmpR and ChlR cells (left panel) as well as in the ratio of AmpR cells to ChlR cells (right panel) under benign conditions. This experimental condition corresponds to 10 μg/ml of ampicillin and 8 μg/ml of chloramphenicol
