Table 1 Control metrics for CL-FES and CL-FOS

From: Closed-loop functional optogenetic stimulation

 

CL-FOS system

n

CL-FES system

n

T-value

P-value

Steady-state root mean squared error for square wave pattern

3.01 ± 1.32%

12

6.31 ± 2.98%

11

3.48

0.0022

Steady-state root mean squared error for sinusoidal wave pattern

1.16 ± 0.93%

12

11.18 ± 4.32%

11

7.85

0.0001

Rise time (ms)

29.7 ± 9.4

62

36.91 ± 8.92

47

4.05

0.0001

Percent overshoot by controller

15.6 ± 7.2

40

45.54 ± 1.07

40

26.02

0.0001

Tsettling (ms)

226 ± 140

36

250 ± 39

20

0.78

0.43

K p

0.08

 

0.5

   

Ti (s)

0.125

 

0.0002

   
  1. Rise time and percent overshoot by the controller are significantly smaller for FOS when compared to FES as per an unpaired t-test at the p = 0.01 level. These data were aggregated from trials performed in virally transduced rats